中科院营养所近年论文一览表

D Wu, Q Zhai, and X Shi. Alcohol-induced oxidative stress and cell responses. J Gastroenterol Hepatol, Oct 2006; 21 Suppl 3: S26-9.

Cai, Q., Zhu, Z., Fan, X., Jia, N., Bai, Z., Song, L.,Li, X., Li, H., and *Liu, J.* (2006) The effects of prenatal stress onkinetic properties of Ca^2+ and K^+ channels in freshly isolated offspring hippocampal CA3 pyramidal neurons. Life Sci. (in press).

Cheng Huang¹, Yuebo Zhang¹, Zhenwei Gong¹, Xiaoyan Sheng, Zongmeng Li, Wei Zhang, Ying Qin. Berberine inhibits 3T3-L1 adipocyte differentiation through the PPARγ pathway. Biochemical and Biophysical Research Communications 348 (2006) 571-578.

Pang SS, Le YY. Role of resistin in inflammation and inflammation-related diseases. Cell Mol Immunol. 2006;3(1):29-34.

Ke Z, Lin H, Fan ZQ, Cai TQ, Kaplan RA, Ma C, Bower KA, Shi X, and Luo J. MMP-2 Partially Mediates Ethanol-induced Invasion of Mammary Epithelial Cells Over-expressing ErbB2. International Journal of Cancer. 119(1):8-16 (2006).

Ke ZJ, Bowen WM, Gibson GE. Inflammatory mechanisms mediate microglial activation but not neurodegeneration in response to mild impairment of oxidative metabolism. Neurochem Intl. (in press) (2006).

Gang Chen, Cuiling Ma, Kimberly A. Bower, Zunji Ke, and Jia Luo. Interaction between RAX and PKR modulates the effect of ethanol on protein synthesis and survival of neurons. J Biol Chem. 2006 Jun 9; 281(23):15909-15. Epub 2006 Mar 29.

Xin Wang¹, Bingwei Wang¹, Zhiqin Fan¹, Xianglin Shi¹, Zun-Ji Ke¹*, and Jia Luo^1,2*. Thiamine Deficiency Induces Endoplasmic Reticulum Stress in Neurons. Neuroscience (in press) (2006).

Gery, S., D. Xie, et al. (2005). Ovarian carcinomas: CCN genes are aberrantly expressed and CCN1 promotes proliferation of these cells. Clin Cancer Res 11(20): 7243-54.

Yin, D., D. Xie, et al. (2006). DLK1: increased expression in gliomas and associated with oncogenic activities. Oncogene 25(13): 1852-61.

Jin, L., Zhou, Y., Kuang, C, Lin, L and Chen, Y. (2005) Expression pattern of TG-interacting factor 2 during mouse development. Gene Expression Patterns (Mechanism of Development) 5,457-62.

Zhou, Y., Sun, X, Jin, L, Stringfield, T, Lin, L and Chen, Y. (2005) Expression profiles of adiponectin receptors in mouse embryos. Gene Expression Patterns (Mechanism of Development) 5,711-5.

Kuang, C., Xiao, Y., Liu, X., Stringfield, T.M., Zhang, S., Wang, Z. and Chen, Y. (2006) In vivo disruption of transforming growth factor-beta signaling by Smad7 leads to premalignant ductal lesions in the pancreas. Proceedings of the National Academy of Sciences of the United States of America 103,1858-63.

Sun, X., Han, R., Wang, Z. and Chen, Y. (2006) Regulation of adiponectin receptors by peroxisome proliferator-activated receptor-gamma agonist rosiglitazone in hepatocytes. Diabetologia 49,1303-10.

Zhou Q, Meng D, Yan B, Jiang BH, and Fang J. Transactivation of epidermal growth factor receptor by insulin-like growth factor 1 requires basal hydrogen peroxide. FEBS Lett. 2006 580:5161-6.

Fang J, Meng Q, Vogt PK, Zhang R, Jiang BH. A downstream kinase of the mammalian target of rapamycin, p70S6K1, regulates human double minute 2 protein phosphorylation and stability. J Cell Physiol. 2006, 209:261-5.

Liu LZ, Fang J, Zhou Q, Hu XW, Shi XL, Jiang BH. Apigenin inhibits expression of vascular endothelial growth factor and angiogenesis in human lung cancer cells: implication of chemoprevention of lung cancer. Mol Pharmacol. 2005, 68:635-43.

Gao N, Zhang Z, Shi XL, Jiang BH. Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer. Biochem Biophys Res Commun. 2003 310:1124-32.

Cao Z, Fang J, Xia C, Shi XL, Jiang BH. trans-3,4,5'-Trihydroxystibene inhibits hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in human ovarian cancer cells. Clin Cancer Res. 2004. 10:5253-63.

Gan Z, Zhao L, Yang L, Huang P, Zhao F, Li W, Liu Y. RNA editing by ADAR2 is metabolically regulated in pancreatic islets and beta -cells. J Biol Chem. 2006 Sep 6; [Epub ahead of print] PMID: 16956888 [PubMed - as supplied by publisher]

Jia,L., Liu,Z., Sun,L., Miller,S.S., Cotman,C.W., Ames,B.N., and Liu,J. : Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in retinal pigment epithelial cells:Protection by (R)--lipoic acid.Invest.  Ophthalmol. Vis. Sci. (in press), 2006.

Cui X, Zuo P, Zhang Q, Li X, Hu Y, Long J, Packer L, Liu J.: Chronic systemic D-galactose exposure induces memory loss, neurodegeneration, and oxidative damage in mice: protective effects of R-alpha-lipoic acid. J Neurosci Res. 2006 Jun;83(8):1584-90.

Sun L, Luo C, Long J, Wei D, Liu J.: Acrolein is a mitochondrial toxin: Effects on respiratory function and enzyme activities in isolated rat liver mitochondria. Mitochondrion. 2006 Jun;6(3):136-142.

Luo C, Wang X, Long J, Liu J.: An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates. J Biochem Biophys Methods. 68:101-111, 2006.

Ke Z, Lin H, Fan ZQ, Cai TQ, Kaplan RA, Ma C, Bower KA, Shi X, and Luo J. MMP-2 Partially Mediates Ethanol-induced Invasion of Mammary Epithelial Cells Over-expressing ErbB2. International Journal of Cancer. 119(1):8-16 (2006).

Ke ZJ, Bowen WM, Gibson GE. Inflammatory mechanisms mediate microglial activation but not neurodegeneration in response to mild impairment of oxidative metabolism. Neurochem Intl. (in press) (2006).

Jing Wang, Qiwei Zhai, Ying Chen, Estelle Lin, Wei Gu, Michael W. McBurney, and Zhigang He. A local mechanism mediates NAD-dependent protection of axon degeneration. The Journal of Cell Biology 170 (1): 349-355.

Qiong Zhou, Ling-Zhi Liu, Beibei Fu, Xiaowen Hu, Xianglin Shi , Jing Fang, and Bing-Hua Jiang. Reactive Oxygen Species Regulate Insulin-induced VEGF and HIF-1a Expression through the Activation of p70S6K1 in Human Prostate Cancer Cells. Carcinogenesis (In press).

Long J, Wang X, Gao H, Liu Z, Liu C, Miao M, Liu J.: Malonaldehyde acts as a mitochondrial toxin: Inhibitory effects on respiratory function and enzyme activities in isolated rat liver mitochondria. Life Sci. 2006 May 7; 79:1466-1472.

Chen G, Ma C, Bower KA, Ke Z, Luo J. Interaction between RAX and PKR Modulates the Effect of Ethanol on Protein Synthesis and Survival of Neurons (in press).

Liu LZ, Fang J, Zhou Q, Hu X, Shi X, Jiang BH. Apigenin inhibits expression of vascular endothelial growth factor and angiogenesis in human lung cancer cells: implication of chemoprevention of lung cancer. Mol Pharmacol. 68:635-643(2005).

Le Y, Yu X, Ruan L, Wang O, Qi D, Zhu J, Lu X, Kong Y, Cai K, Pang S, Shi X, Wang JM. The Immunopharmacological properties of transforming growth factor beta. International Immunopharmacology. 5(13-14):1771-1782(2005).

St. Clair D. Xu M., Wang P., Yu Y., Fang Y., Zhang F., Zheng X., Gu N., Feng G., Sham P. and He L.. Rates of Adult Schizophrenia Following Prenatal Exposure to the Chinese Famine of 1959-1961. Journal of the American Medical Association. 294:557-562 (2005)

Yingying Le, Richard D.Ye, Wanghua Gong, Jinyue Hu, Xia Zhang, and Ji Ming Wang. Identification of functional domains in the formyl peptide receptor-like 1 for agonist-induced cell chemotaxis. FEBS Journal 272:769-782 (2005).

Pablo Iribarren, Ye Zhou, Jinyue Hu, Yingying Le, Ji Ming Wang. Role of formyl peptide receptor-like 1 (FPRL1/FPR2) in mononuclear phagocyte responses in Azheimer disease. Immunologic Research 31:165-176 (2005).

Zun-Ji Ke, Noel Y. Calingasan, Saravanan S. Karuppagounder, Lorraine A. DeGiorgio, Bruce T. Volpe, Gary E. Gibson. CD40L Deletion Delays Neuronal Death in a Model of Neurodegeneration Due to Mild Impairment of Oxidative Metabolism. Journal of Neuroimmunology. 164(1-2):85-92 (2005).

Zun-Ji Ke, Noel Y. Calingasan, Lorraine A. DeGiorgio, Bruce T.Volpe, Gar E. Gibson. CD40-CD40L interactions promote neuronal death in a model of neurodegeneration due to mild impairment of oxidative metabolism. Neurochemistry International.47(3):204-215 (2005).

Yadong Zhang, Yongju Lu, Bao-Zhu Yuan, Vince Castranova, Xianglin Shi, John L Stauffer, Laurence M Demers and Fei Chen. The human mineral dust-induced gene, mdig, is a novel cell growth regulating gene associated with lung cancer. Oncogene. 24(31):4873-82(2005).

Xue Zheng, Yadong Zhang, Yu-quan Chen, Vince Castranova, Xianglin Shi, Fei Chen. Inhibition of NF-kB stabilizes gadd45a mRNA. Biochemical Biophysical Research Communications 329:95-99 (2005).

Lin Lin, Yong Qian, Xianglin Shi, and Yan Chen. Induction of a cell stress response gene RTP801 by DNA damaging agent methylmethane sulfonate through CCAAT/Enhancer Binding Protein. Biochemistry 44:3909-3914 (2005).

Lei Jin, Yunhua Zhou, Chenzhong Kuang, Lin Lin, Yan Chen. Expression pattern of TG-interacting factor 2 during mouse development. Gene Expression Patterns 5:457-462 (2005).

Yunhua Zhou, Xiaolan Sun, Lei Jin, Teresa Stringfield, Lin Lin, Yan Chen. Expression profiles of adiponectin receptors in mouse embryos. Gene Expression Patterns 5:711-715 (2005).

Li Bian, Jian Dong Yang, Ting Wei Guo, Yun Duan, Wei Qin, Yun Sun, Guo Yin Feng, and Lin He. Association study of the A2M and LRP1 genes with alzheimer disease in the Han Chinese. Biological Psychiatry (in press).

Qinghe Xing, Xiangdong Chen, Mingtai Wang, Wenjie Bai, Xin Peng, Rui Gao, Shengnan Wu, Xueqing Qian, Wei Qin, Jianjun Gao, Guoyin Feng and Lin He. A locus for familial generalized lentiginosis without systemic involvement maps to chromosome 4q21.1=q22.3. Human Genetics (in press).

Hai-Tao Zheng, Zhi-Hai Peng, Chong-Zhi Zhou, Da-Peng Li, Zhao-Wen Wang, Guo-Qiang Qiu, Lin He. Detailed deletion mapping of loss of heterozygosity on 22q13 in sporadic colorectal cancer. World Journal of Gastroenterology (in press).

Qi Chen, Guang He, Qingying Chen, Shengnan Wu, Yifeng Xu, Guoyin Feng, Yucheng Li,Lijun Wang, Lin,He. A case-control study of the relationship between the metabotropic glutamate receptor 3 gene and schizophrenia in the Chinese population. Schizophrenia Research 73:21-26 (2005).

Qing-Ying Chen, Qi Chen, Guo-Yin Feng, Klaus Lindpaintner, Yi Chen, Xiaodong Sun, Zhengxiong Chen, Zhensong Gao, Jisheng Tang, Lin He. Case-control association study of the close homologue of L1 (CHL1) gene and schizophrenia in the Chinese population. Schizophrenia Research 73:269-274 (2005).

Shiwei Duan, Rui Gao, Qinhe Xing, Jing Du, Zhuangjun Liu, Qi Chen, Hongsheng Wang, Guoyin Feng, Lin He. A family-based association study of schizophrenia with polymorphisms at three candidate genes. Neuroscience Letters 379:32-36 (2005).

Shiwei Duan, Hua Yin, Wuyan Chen, Qinhe Xing, Qi chen, Tingwei Guo, Jianjun Gao, Xiuxia Li, Rui Gao , Zhuangjun Liu, Niufan Gu, Guoyin Feng, Lin He. No association between the serotonin 1B receptor gene and schizophrenia in a case-control and family-based association study. Neuroscience Letters 376:93-97 (2005).

Ting-Wei Guo, Fu-chang Zhang, Jian-jun Gao, Li Bian, Xiao-cai Gao, Jie Ma, Maosheng Yang, Qian Ji, Shi-wei Duan, Zi-jian Zheng, Rui-jian Li, Guo-yin Feng, David St.Clair, Lei He. Polymorphisms in the TSHR (thyrotropin receptor) gene on chromosome 14q31 are not associated with mental retardation in the iodine-deficient areas of China. Neuroscience Letters 382:179-184 (2005).

Xinmin Liu, Wei Qin, Guang He, Yifeng Yang, Qi Chen, Jian Zhou, Dawei Li, Niufan Gu, Yifeng Xu, Guoyin Feng, Hong Sang, Xinming Hao, Kui Zhang, Shiji Wang, Lin He. A family-based association study of the MOG gene with schizophrenia in the Chinese population. Schizophrenia Research 73:275-280 (2005).

Jixia Liu, Yongyong Shi, Junxia Tang, Tingwei Guo, Xiuxia Li, Yifeng Yang, Qingying Chen, Xinzhi Zhao , Guang He, Guoyin Feng, Niufan Gu, Shaomin Zhu, Huijun Liu, Lin He. SNPs and haplotypes in the S100B gene reveal association with schizophrenia. Biochemical and Biophysical Research Communications 328:335-341 (2005).

Yu-xi Pan, Da-Wei Li, Yun Duan, Zhi-Zhou Zhang, Ming-Qing Xu, Guo-Yin Feng, and Lin He. Predicting protein subcellular location using digital signal processing. Acta Biochimica et Biophysica Sinica 37:88-96 (2005).

Wei Qin, Jianjun Gao, Qinghe Xing, Jiandong Yang, Xueqing Qian, Xingwang Li, Zhongmeng Guo, Helong Chen, Linjun Wang, Xuangyin Huang, Niufen Gu, Guoyin Feng, Lin He. A family-based association study of PLP1 and schizophrenia. Neuroscience Letters. 375:207-210 (2005).

Yong Yong Shi, Lin He. SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci. Cell Research 15:97-98 (2005).

Shengnan Wu, Qinhe Xing, Rui Gao, Xingwang Li, Niufan Gu, Guoyin Feng, Lin He. Response to chlorpromazine treatment may be associated with polymorphisms of the DRD2 gene in Chinese schizophrenic patients. Neuroscience Letters 376:1-4 (2005).

Y.F. Yang, W.Qin, Y.Y. Shugart, G. He, X.M. Liu, J. Zhou, X.Z. Zhao, Q. Chen, Y.J. La, Y.F. Xu, X.W. Li, N.F. Gu, G.Y. Feng, H. Song, P. Wang, L. He. Possible association of the MAG locus with schizophrenia in a Chinese Han cohort of family trios. Schizophrenia Research 75:11-19 (2005).

Linghan Gao, Wei Qin, Hao Cui, Guoyin Feng, Ping Liu, Weiqi Gao, Lin Ma, Pu Li, Lin He and Songbin Fu. A Novel Locus of Coralliform Cataract Mapped to Chromosome 2p24-pter. Journal of Human Genetics (in press).

Shengying Qin, Xu Zhao, Yuxi Pan, Jianhua Liu, Guoyin Feng, Jingchun Fu, Jiying Bao, Zhizhou Zhang and Lin He. An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray. European Journal of Human Genetics (in press).

Yonglan Zheng, Huafang Li, Wei Qin, Wuyan Chen, Yun Duan, Yue Xiao, Chao Li, Jing Zhang, Xingwang Li , Guoyin Feng, Lin He. Association of the carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase gene with schizophrenia in the Chinese Han population. Biochemical and Biophysical Research Communications 328:809-815 (2005).

Fanggeng Zou, Chao Li, Shiwei Duan, Yonglan Zheng, Niufan Gu, Guoyin Feng, Yangling Xing, Jianguo Shi , Lin He. A family-based study of the association between the G72/G30 genes and schizophrenia in the Chinese population. Schizophrenia Research 73:257-261 (2005).

Yingying Le, Pablo Iribarren, Ye Zhou, Wanghua Gong, Jinyue Hu, Xia Zhang, and Ji Ming Wang. Silencing the formylpeptide receptor FPR by short-interfering RNA. Molecular Pharmacology 66:1022-1028 (2004).

Moe Moe Aye, Cuiling Ma, Hong Lin, Kimberly A. Bower, Richard C Wiggins, Jia Luo. Ethanol-induced in vitro invasion of breast cancer cells: the contribution of MMP-2 by fibroblasts. International Journal of Cancer 112:738-746 (2004).

Z. Li, M. Ding, c.J. Thiele and J. Luo. Ethanol inhibits brain-derived neurotrophic factor-mediated intracellular signaling and activator protein-1 activation in cerebellar granule neurons. Neuroscience 126:149-162 (2004).

Gang Chen, Kimberly A. Bower, Cuiling Ma, Shengyun Fang, Carol J. Thiele, Jia Luo. Glycogen synthase kinase 3beta (GSK3β) mediates 6-hydroxydopamine-induced neuronal death. FASEB Journal 18:1162-1164 (2004).

Cuiling Ma, Jin Wang, Jia Luo. Activation of nuclear factor kappa B by diesel exhaust particles in mouse epidermal cells through phosphatidylinositol 3-kinase/Akt signaling pathway. Biochemical Pharmacology 67:1975-1983 (2004).

Zongxian Cao, Jing Fang, Chang Xia, Xianglin Shi, and Bing-Hua Jiang. trans-3,4,5'Trihydroxystibene inhibits hypoxia-inducible factor 1α and vascular endothelial growth factor expression in human ovarian cancer cells. Clinical Cancer Research 10:5253-5263 (2004).

Yadong Zhang and Fei Chen. Reactive Oxygen Species (ROS), Troublemakers between Nuclear Factor-kB(NF-kB) and c-Jun NH2-terminal kinase(JNK). Cancer Research 64:1902-1905 (2004).

Xu Chui, Luning Wang, Pingping Zuo, Zhitao Han, Zhengyu Fang, Wenbin Li and Jiankang Liu. D-Galactose-caused life shortening in drosophila melanogaster and musca domestica is associated with oxidative stress. Biogerontology 5:317-325 (2004).

Zhongliang zhu, Xia Li, Weina Chen, Yan Zhao, Hui Li, Cai Qing, Ning Jia, Zhuanli Bai, and Jiankang Liu. Prenatal stress causes gender-dependent neuronal loss and oxidative stress in rat hippocampus. Journal of Neuroscience Research 78:837-844 (2004).

Ying Peng, Bing-Hua Jiang, Pai-Hao Yang, Zongxian Cao, Xianglin Shi,Marie C.M Lin, Ming-Liang He, and Hsiang-Fu Kung. Phosphatidylinositol-3 kinase signaling is involved in neurogenesis during Xenopus embryonic development. Journal of Biological Chemistry 279:28509-28514 (2004).

Jingxia Li, Haobin Chen, Moon-Shong Tang, Xianglin Shi, Shantu Amin, Dhimant Desai, Max Costa, and Chuanshu Huang. PI-3K and akt are mediators of AP-1 induction by 5-methylacrysene-1,2-diol-3,4-epoxide (5-MCDE) in mouse epidermal C141 cells. Journal of Cell Biology 165:77-86 (2004).

Jingxia Li, Gerard Davidson, Yi Huang, Bing-Hua Jiang, Xianglin Shi, Max Costa, and Chuanshu Huang. Nickel Compounds Acts through PI-3K/Akt-dependent, p70S6k-independent Pathway to induce HIF Transactivation and Cap43 Expression in Mouse epidermal Cl41 cells. Cancer Research 64: 94-101 (2004).

Qiwei Zhai, Yi Luo, Ye Zhang, Michael A. Berman, and Martin E. Dorf. Low nuclear levels of nuclear factor-kappa B are essential for KC self-induction in astrocytes: requirements for shuttling and phosphorylation. Glia 48:327-336 (2004).

Dong Xie, Dong Yin, Xiangjun Tong, James O’Kelly, Carl Miller, Johathan W. Said, Keith Black and H. Phillip Koeffler. Cyr61 is an oncogene in gliomas which stimulates the Integrin linked kinase mediated b-catenin-TCF/Lef and Akt signaling pathways. Cancer Research 64:1987-1996 (2004).

Dong Xie, Dong Yin, Heming Wang, Robert Elashoff, Keith Black and H. Phillip Koeffler. Levels of expression of Cyr61 and CTGF are prognostic for tumor progression and survival of individuals with Gliomas. Clinical Cancer Research 10:2112-2121 (2004).

Dong Yin, Dong Xie, Seven DeVos, Gentao Liu, Carl Miller, Keith Black and H. Phillip Koeffler. Imprinting status of DLK1 gene in brain tumors and lymphomas. International Journal of Oncology 24:1011-1016 (2004).

Xiangjun Tong, James O'Kelly, Dong Xie, Akio Mori, Nathan Lemp, Robert McKenna, Carl W Miller, and H. Phillip Koeffler. Cyr61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway. Oncogene 23:4847-4855 (2004).

Gentao Liu, John S.Yu, Gang Zeng, Dong Yin, Dong Xie, Keith L.Black, Han Ying. AIM-2: A novel tumor antigen is expressed and presented by human glioma cells. Journal of Immunotherapy 27:220-226 (2004).

Chenzhong Kuang,and Yan Chen. Tumor-derived C-terminal mutations of Smad4 with decreased DNA binding activity and enhanced intramolecular interaction. Oncogene 23:1021-1029 (2004).

Kenji Ogawa, Feifei Chen, Chenzhong Kuang, and Yan Chen. Suppression of matrix metalloproteinase-9 transcription by transforming growth factor-beta is mediated by a NF-kappaB site. Biochemical Journal 381:413-422 (2004).

Qi Chen, Guang He, Wei Qin, Qing-ying Chen, Xin-zhi Zhao, Shi-wei Duan, Xin-min Liu, Guo-yin Feng, Yi-feng Xu, David St Clair,Min Li,Jin-huan Wang, Yang-ling Xing, Jian-guo Shi, and Lin He. Family-based association study of synapsin II and schizophrenia. American Journal of Human Genetics 75:873-877 (2004).

Qi Chen, Guang He, Xiao Yan Wang, Qing Ying Chen, Xin Min Liu, Zhong Zhong Gu, Jie Liu, Ke Qing Li, Shi Ji Wang, Shao Ming Zhu, Guo Ying Feng, and Lin He. Positive Association Between Synapsin II and Schizophrenia. Biological Psychiatry 56:177-181 (2004).

Wuyan Chen, Shiwei Duan, Jian Zhou, Yun Sun, Yonglan Zheng, Niufan Gu, Guoyin Feng, and Lin He. A case-control study provides evidence of association for a functional polymorphism –197C/G in XBP1 to schizophrenia and suggests a sex-dependent effect. Biochemical and Biophysical Research Communications 319:866-870 (2004).

Wuyan Chen, Niufan Gu, Shiwei Duan, Yun Sun, Yonglan Zheng, Chao Li, Yuxi Pan, Yifeng Xu, Guoyin Feng , Lin He. No association between the genetic polymorphisms within RTN4 and schizophrenia in the Chinese population. Neuroscience Letters 365:23-27 (2004).

Wu-Yan Chen, Yong-Yong Shi, Yong-Lan Zheng, Xin-Zhi Zhao, Guang-Ji Zhang, Sheng-Qi Chen, Pei-Di Yang and Lin He. Case–control study and transmission disequilibrium test provide consistent evidence for association between schizophrenia and genetic variation in the 22q11 gene ZDHHC8. Human Molecular Genetics 13:2991-2995 (2004).

Shiwei Duan, Yifeng Xu, Wuyan Chen, Zhuangjun Liu, Tingwei Guo, Jianjun Gao, Li Bian, Yonglan Zhen , Xiuxia Li, Xiaoju Zhang, Yuxi Pan, Niufan Gu, Guoyin Feng, Lin He. No association between the promoter variants of tumor necrosis factor alpha (TNF-alpha) and schizophrenia in Chinese Han population. Neuroscience Letters 366:139-143 (2004).

Jin-Bo Fan, Chang-Shun Zhang, Niu-Fan Gu, Xing_Wang Li, Wei-Wei Sun, Hong-Yan Wang, Guo-Yin Feng, David St Clair, and Lin He. Catechol-O-methyltransferase gene Val/Met functional polymorphism and risk of schizophrenia: a large-scale association study plus meta-analysis. Biological Psychiatry 57:139-144 (2004).

Jin-Bo Fan, Mao-Sheng Yang, Jun-Xia Tang, Yang-Ling Xing, Jian-Guo Shi, Shu-Min Zhao, Si-Min Zhu, Li-Pin Ji, Niu-Fan Gu, Guo-Ying Feng, David St Clair, and Lin He. Family-based association study of the functional monoamine oxidase A gene (MAOA) promoter polymorphism and schizophrenia. Schizophrenia Research 67:107-109 (2004).

Bo Gao, Lin He. Answering a century old riddle: brachydactyly type A1. Cell Research 14:179-187 (2004).

Jianjun Gao, Fuchang Zhang, Tinwei Guo, XiaoCai Gao, Shiwei Duan, Hongyan Wang, Zijan Zheng, Tiezhu Huang, Guoyin Feng, D.St Clair and Lin He. Distribution of apolipoprotein E allele frequencies of the Han Chinese in an iodine-deficient mountainous area. Annals of Human Biology 31:578-585 (2004).

Shengzhen Guo, Yongyong Shi, Xinzhi Zhao, Shiwei Duan, Jioan Zhou, Junwei Meng, Yifeng Yang, Niufan Gu, Guoyin Feng, Huijun Liu, Shaomin Zhu, Lin He. No genetic association between polymorphisms in the AMPA receptor subunit GluR4 gene(GRIA4) and schizophrenia in the Chinese population. Neuroscience Letters 369:168-172 (2004).

T-W Guo, F-C Zhang, M-S Yang, X-C Gao, L Bian, S-W Duan, Z-J Zheng, J-J Gao, H Wang, R-L Li, G-Y Feng, D St Clair, L He. Positive association of the DIO2 (deiodinase type 2) gene with mental retardation in the iodine-deficient areas of China. Journal of Medical Genetics 41:585-590 (2004).

Da-Wei Li, YU-Xi Pan, Yun Duan, Zhen-De Huang, Ming-Qing Xu, and Lin He. Understanding SARS with Wolfram Approach. Acta Biochimica et Biophysica Sinica 36:1-10 (2004).

Xinmin Liu, Guang He, Xiaoyan Wang, Qi Chen, Xueqing Qian, Wei Lin, Dawei Li, Niufan Gu,Guoyin Feng ,Lin He. Association of DAAO with schizophrenia in the Chinese population. Neuroscience Letters 369:228-233 (2004).

Xueqing Qian, Anli Shu,Wei Qin, Qinhe Xing, Jianjun Gao, Jiandong Yang, Guoyin Feng, Lin He. A novel insertion mutation in the FOXL2 gene is detected in a big Chinese family with blepharophimosis-ptosis-epicanthus inversus. Mutation Research 554:19-22 (2004).

Yifeng Shen, Huafang Li, Niufan Gu, Zheng Tan, Junxia Tang, Jinbo Fan, Xingwang Li, Wei Sun, Lin He. Relationship between suicidal behavior of psychotic inpatients and serotonin transporter gene in Han Chinese. Neuroscience Letters 372:94-98 (2004).

YongYong Shi, Xinzhi Zhao, Lan Yu, Ran Tao, JunXia Tang, YuJuan La, Yun Duan, Bo Gao, NiuFan Gu, YiFeng Xu,GuoYin Feng, ShaoMin Zhu, HuiJun Liu, Hugh Salter, and Lin He. Genetic Structure Adds Power to Detect Schizophrenia Susceptibility at SLIT3 in the Chinese Han Population. Genome Research 14:1345-1349 (2004).

JX Tang, WY Chen, G He, J Zhou, NF Gu, GY Feng and L He. Polymorphisms within 5' end of the Neuregulin 1 gene are genetically associated with schizophrenia in the Chinese population. Molecular Psychiatry 9:11-13 (2004).

Xiaoyan Wang, Guang He, Niufan Gu, Jiandong Yang, Junxia Tang, Qi Chen, Xinmin Liu, Yifeng Shen, Xueqing Qian, Wei Lin, Yun Duan, Guoyin Feng, and Lin He. Association of G72/G30 with Schizophrenia in the Chinese population. Biochemical and Research Communications 319:1281-1286 (2004).

Z.R.Xi, W.Qin W, Y.F.Yang, G.He, S.H.Gao, M.S.Ren, Y.W.Peng, Z.Zhang, L.He. Transmission disequilibrium analysis of the GSN gene in a cohort of family trios with schizophrenia. Neuroscience Letters 372:200-203 (2004).

M S Yang, L Yu, T W Guo, S M Zhu, H J Liu, Y Y Shi, N F Gu, G Y Feng, L He. Evidence for association between single nucleotide polymorphisms in T complex protein 1 gene and schizophrenia in the Chinese Han population. Journal Medical Genetics 41:1-5 (2004).

Yifeng Yang, Zeping Xiao, Weixiong Chen, Hong Sang, Yousheng Guan, Yanwei Peng, Diran Zhang, Zhongzhong Gu, Mincai Qian, Guang He, Wei Qin, Dawei Li, Niufan Gu NF, Lin He. Tumor suppressor gene TP53 is genetically associated with schizophrenia in the Chinese population. Neuroscience Letters 369:126-131 (2004).

L Yu, T Li, Z Robertson, J Dean, NF Gu, GY Feng, P Yates, M Sinclair, C Crombie, DA Collier, N Walker , L He L and D Sr Clair. No association between polymorphisms of methylenetetrahydrofolate reductase gene and schizophrenia in both Chinese and Scittish populations. Molecular Psychiatry 9:1063-1065 (2004).

Lan Yu, Mao-sheng Yang, Jian Zhao, Yong-yong Shi, Xin-zhi Zhao, Jian-dong Yang, Zhuang-jun Liu, Niu-fan Gu, Guo-yin Feng, Lin He. An association between polymorphisms of the interleukin-10 gene promoter and schizophrenia in the Chinese population. Schizophrenia Research 71:179-183 (2004).

Chang-shun Zhang, Zheng Tan, Lan Yu, Sheng-nan Wu, Ying He, Niu-fan Gu, Guo-yin Feng, Lin He. Polymorphism of Prodynorphin promoter is associated with schizophrenia in Chinese population. Acta Pharmacologica Sinica 25:1022-1026 (2004).

L.Bian, J.D.Yang, T.W.Guo, Y.Sun, S.W.Duan, W.Y.Chen, Y.X.Pan, G.Y.Feng, and L.He. Insulin-degrading enzyme and Alzheimer’s disease: a genetic association study in the Han Chinese. Neurology 63:241-245 (2004).

X Zhao, Y Shi, J Tang, R Tang, L Yu, N Gu, G Feng, S Zhu, H Liu, Y Xing, S Zhao, H Sang, Y Guan, D St Clair, L He. A case control and family based association study of the neuregulin 1 gene and schizophrenia. Journal Medical Genetics 41:31-34 (2004).

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